药学前沿大讲堂第84讲-Nuclear Receptors-mediated Crosstalk between Drug Metabolism and Energy Metabolism

报告题目：Nuclear Receptors-mediated Crosstalk between Drug Metabolism and Energy Metabolism

主 讲 人：　谢文 教授

美国匹兹堡大学 University of Pittsburgh

主 持 人：  黄民 教授  

威廉希尔williamhill官方网站药学院

讲座时间：  2011年4月27日（星期三）上午10:00

讲座地点：  威廉希尔williamhill官方网站东校区药学大楼125讲学厅

谢文教授简介：

Wen Xie (MD, PhD) is currently Professor of Pharmaceutical Sciences and Pharmacology. Dr. Xie obtained his MD degree from Peking University Health Science Center in 1991, and PhD in Cell Biology from University of Alabama at Birmingham in 1997. He completed a postdoctoral fellowship (1998-2002) with Dr. Ronald M. Evans at the Salk Institute in La Jolla, California. Dr. Xie joined the University of Pittsburgh in 2002. Dr. Xie holds joint appointment at the Center for Pharmacogenetics and Department of Pharmaceutical Sciences at the School of Pharmacy and Department of Pharmacology and Chemical Biology at the School of Medicine. The research focus of Dr. Xie's laboratory is nuclear receptor-mediated transcriptional regulation of genes that encode drug metabolizing enzymes and drug transporters. This regulation has broad implications in drug metabolism and many human diseases, including hepatobiliary diseases, endocrine disorders, metabolic syndrome, and cancers. Dr. Xie’s research is conducted using a combination of cell cultures and genetically engineered mice that include transgenic, knockout and humanized mice. Dr. Xie is the author or coauthor of nearly 80 journal articles and book chapters and over 90 invited lectures at conferences and universities. Dr. Xie is the sole editor of "Nuclear Receptors in Drug Metabolism", a book published by Wiley in 2008. Dr. Xie currently serves as ad hoc reviewer for NIH and DOD Study Sections and for over 20 scientific journals. Among his achievements, Dr. Xie is the recipient of the University of Pittsburgh Chancellor’s Distinguished Research Award, the James R. Gillette International Society for the Study of Xenobiotics (ISSX) North American New Investigator Award, and the American Society for Pharmacology and Experimental Therapeutics (ASPET) Division for Drug Metabolism Early Career Achievement Award.

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